Ameliorative Effect of Young Leaves of Triticum Aestivum on Carrageenin Induced Inflammation

Young leaves of Triticum aestivum is commonly known as Wheatgrass and has been widely used in the traditional system for the treatment of a variety of diseases. In this study we have used ninth day wheat grass methanolic extract of the shade dried drug for its anti-inflammatory & analgesic activities. . It was carried out using Carrageenan induced paw edema volume, Hot plate and Writhing response model which is comparable with standard drug. The methanolic fraction of the grass extract of Triticum aestivum (500 mg/kg) showed the significant inhibition of carrageenin induced rat paw oedema at the end of fourth hour. The extract also significantly reduced thermal and chemical induced nociception (Hot plate and writhing response) in mice when compared with vehicle treated group. The results prove that the methanolic fraction of the grass extract of Triticum aestivum showed anti-inflammatory activity and analgesic activity in acute inflammation and also proved the usage of traditional claims.